Posted by: LifeNet Health on Feb 25, 2019
Virginia Beach, VA
The LifeNet Health mission is simple: Saving Lives. Restoring Health. Giving Hope. Its mission, along with its core values of safety, quality, innovation and service continue to create an unmatched record in transplant solutions, which cannot be achieved without talented, dedicated team members who share the same values and attributes that guide the LifeNet Health team every day.
If you have a commitment to customer care, quality and innovation as well as integrity and passion, then you've come to the right place.
We are currently seeking a Life Sciences Hepatic R&D Scientist to join the LifeNet Health team in our Concert Drive, Virginia Beach, Virginia location.
The R&D Scientist leads and coordinates the development and validation of in vitro cell-based models of healthy and diseased human liver for biomedical and pharmaceutical research applications. Model development and validation of system performance specifications will involve the use of biochemical/molecular assays for basic liver functions, metabolic bioactivation pathways, cell-cell interactions and other endpoint parameters, such as extracellular matrix chemistry, hemodynamic flow, and stem cell populations. Other related activities include development of a suite of in vitro biomarkers of healthy and diseased hepatocytes and non-parenchymal cells, conducting hepatotoxicity experiments with well-studied compounds using state-of-the-art analytical approaches, to demonstrate the fidelity of new culture systems for in vitro-in vivo extrapolations and strategies for human risk assessment. R&D Scientists develop intellectual property in support of divisional project portfolios.
A PhD degree in Bioengineering, Cell/Molecular Biology, Biochemistry or a related discipline plus 7 years related work experience is preferred. Candidates with a Master's Degree plus 5 years related work experience will be considered. Experience with primary hepatocytes and/or non-parenchymal cell isolation and culture, or development of advanced tissue culture model systems using primary cells is preferred. Previous experience with the establishment, implementation, and data interpretation of standard molecular biology, biochemical and cell biology assays for preclinical drug development or investigative toxicology, such as qPCR, fluorescent, luminescent, and various spectroscopic techniques.
You would be expected to perform all tasks assigned to you, including but not limited to:
Leads and coordinates research efforts for R&D projects based on corporate prioritiesPlans and executes laboratory research as outlined in experimental design of project and in compliance with written policies.Develops assays and protocols pertaining to research and product development objectives as neededMakes detailed observations, analyzes data, interprets results and summarizes collected data into effective technical reports.Provides timely and effective communication (written and oral) of procedures, observations, and results.Develops techniques and technologies needed to develop clinical or research productsInvestigated the feasibility of the potential invention s and products.Assists in the development of intellectual property in support of the divisional project portfolio.Conducts appropriate literature reviews and assists in identifying opportunities for research projects for new products.Trains research associates and technicians on developed assays and protocols and provides scientific support to their experimental design and technical report. Minimum Qualifications:
Master's Degree in Life Sciences, Biomedical Engineering or related field5 years related work experienceProficient in Laboratory skillsProficient in Microsoft OfficePreferred Qualifications:
PhD in Life Sciences, Biomedical Engineering or related field7 years related work experiencePrevious experience in Tissue Banking, Medical Device or related industryGet to Know LifeNet Health:
LifeNet Health, headquartered in Virginia Beach, Virginia, is the largest nonprofit organ procurement organization ("OPO") and tissue bank in the United States, as well as a leading innovator in transplantation research and regenerative medicine. LifeNet holds the longest running current accreditation by the American Association of Tissue Banks (AATB). Its goal is to improve the quality of human life through the provision of organs and tissues for transplantation, as well as innovation in the fields of bio-implants and regenerative medicine, and to serve the community with educational and support services that enhance the donation process.
We are proud to be an EEO/AA employer EOE/M/F/Disability/Vet. We maintain a drug-free workplace and perform pre-employment substance abuse testing.
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